The role of Exercise as an anti-inflammatory therapy for patients with Osteoarthritis and Rheumatoid arthritis

Poster Presentation
Paper ID : 1274-SSRC
Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, Allameh Tabataba’I University, Tehran, Iran
Background: Osteoarthritis (OA) and Rheumatoid arthritis (RA) are the most common type of arthritis and cause painful, swollen, and stiff joints. In 2019, about 528 million people worldwide were living with osteoarthritis; an increase of 113% since 1990 and 18 million people worldwide were living with rheumatoid arthritis. Tumor Necrosis Factor-alpha (TNF-α), Interleukin 6 (IL-6), and C-Reactive Protein (CRP) as pro-inflammatory cytokines increase in these patients. Exercise is an effective intervention to improve the inflammatory condition through the regulation of cytokines.
Aim: This review study was undertaken to assess the impact of diverse exercise modalities on inflammatory markers in individuals diagnosed with OA and RA.
Methodology: In this study, we examined a subset of original articles that were retrieved from PubMed, Google Scholar, and databases and focused on the impact of exercise on inflammatory markers in individuals with OA and RA.
Results: The exercise modalities employed included aerobic, resistance, combined, and interval training, predominantly administered on a thrice-weekly basis.
Conclusion: Exercise not only does not increase inflammation but also decreases inflammatory processes, especially in the case of TNF-α and CRP factors in people with OA and RA. nevertheless, exercise prescription has to be tailored to the patient’s functional limitations, performances, and baseline levels of cardiorespiratory fitness. Exercise therapies of different types, durations, and intensities can be clinically effective inflammation of RA and OA. However, Exercise for relatively longer periods can decrease inflammatory activity better. Therefore, exercises can be used along with other therapeutic interventions such as pharmaceutical and nutritional interventions to control the inflammatory condition of patients with OA and RA.