Co-administration of exercise training and vitamin D on muscle strength in older adult: a systematic reviews and meta-analysis

Poster Presentation
Paper ID : 1336-SSRC
1دانشگاه کاشان
2دانشگاه کاشان دانشکده علوم انسانی گروه علوم ورزشی
Introduction. Ageing is associated with loss of muscle strength, which contributes to the development of chronic diseases. Exercise training could be effective for preventing sarcopenia and thus a viable intervention in ageing. In addition, Vitamin D supplementation may be contribute to increase muscle strength. Therefore, we performed a systematic review and meta-analysis to investigate the effects of adding vitamin D to exercise training on muscle strength in older adults (≥65 years).
Method. A comprehensive search was conducted in three main database including PubMed, Web of Science and Scopus to identify original studies comparing effect of exercise training versus exercise training alone on upper and lower-body muscle strength in older adults with mean ages ≥ 65 years old. The search were conducted using three main key words i.e. "exercise training", "muscle strength", and "elderly". Standardized mean difference (SMD) and 95% confidence interval were used to determine the effect size using CMA3. Also, I2 test was used to evaluate heterogeneity and Egger's test and visual interpretation of funnel plot were used to assesses publication bias.
Results. Eleven studies including 1242 elderly adults were included in the meta-analysis. Our results show that adding vitamin D supplementation to exercise training significantly increased upper-body muscle strength [0.38 (CI: 0.02 to 0.74), p=0.03]; however, had not significant effect on lower-body muscle strength [-0.16 (CI: -0.46 to 0.13), p=0.28].
Conclusion: In older adults, adding vitamin D to exercise training may improve muscle strength, which may be contribute to prevent aging related sarcopenia. Further studies are needed to confirm the synergetic effect of adding vitamin D, and studies should also investigate its role on muscle mass.