The effect of caloric restriction and aerobic exercise on visceral fat in type 2 diabetic male rats
Poster Presentation
Paper ID : 1412-SSRC
Authors
1دانشگاه گیلان
2آموزش و پرورش
Abstract
Abstract:
Background and Purpose: Aerobic exercises and low-calorie diet (calorie restriction) are often prescribed for weight loss in obesity. While changes in body weight are commonly used to evaluate lifestyle interventions, visceral obesity (VAT) is a more relevant and powerful predictor of morbidity and mortality. Several international guidelines recommend lifestyle interventions aimed at reducing body weight by 5-10% as a treatment for obesity. Changes in visceral fat may occur regardless of changes in body weight. A low-calorie diet reduces skeletal muscle mass, which, along with reducing fat mass, helps in weight loss. But aerobic exercise may be associated with an increase in lean body mass or plasma volume. Assuming a reduction in body fat mass with exercise, exercise may still not lead to weight loss by increasing muscle mass.
Methodology: In this research, 32 Wistar male rats with an approximate age of 4 weeks and an average weight of 139.8±4.9 grams were randomly selected as research samples. Animals on a high-fat diet for 4 weeks cause insulin resistance and STZ injection causes beta-cell dysfunction and type 2 diabetes. Sports intervention for the training group was carried out for 8 weeks, 5 sessions per week. According to the research protocol, during the period of negative energy balance, 25% of the average daily energy intake is deducted. This research has been approved by the Ethics Committee of the Research Institute of Physical Education and Sports Sciences of Iran with the ethics code IR.SSRI.REC.1401.1358.
Results: Our results confirm that both caloric restriction and exercise training successfully reduce visceral adipose tissue. A low-calorie diet resulted in significantly more weight loss. Compared to caloric restriction, exercise shows a greater decrease in visceral fat tissue. These results are significant (p≤.05).
Conclusion: We found that calorie restriction has a greater effect on weight loss than exercise. But in fact, aerobic exercise had a better effect on reducing visceral fat tissue compared to calorie restriction. This shows the superiority of aerobic exercise in insulin sensitivity and diabetes.
Background and Purpose: Aerobic exercises and low-calorie diet (calorie restriction) are often prescribed for weight loss in obesity. While changes in body weight are commonly used to evaluate lifestyle interventions, visceral obesity (VAT) is a more relevant and powerful predictor of morbidity and mortality. Several international guidelines recommend lifestyle interventions aimed at reducing body weight by 5-10% as a treatment for obesity. Changes in visceral fat may occur regardless of changes in body weight. A low-calorie diet reduces skeletal muscle mass, which, along with reducing fat mass, helps in weight loss. But aerobic exercise may be associated with an increase in lean body mass or plasma volume. Assuming a reduction in body fat mass with exercise, exercise may still not lead to weight loss by increasing muscle mass.
Methodology: In this research, 32 Wistar male rats with an approximate age of 4 weeks and an average weight of 139.8±4.9 grams were randomly selected as research samples. Animals on a high-fat diet for 4 weeks cause insulin resistance and STZ injection causes beta-cell dysfunction and type 2 diabetes. Sports intervention for the training group was carried out for 8 weeks, 5 sessions per week. According to the research protocol, during the period of negative energy balance, 25% of the average daily energy intake is deducted. This research has been approved by the Ethics Committee of the Research Institute of Physical Education and Sports Sciences of Iran with the ethics code IR.SSRI.REC.1401.1358.
Results: Our results confirm that both caloric restriction and exercise training successfully reduce visceral adipose tissue. A low-calorie diet resulted in significantly more weight loss. Compared to caloric restriction, exercise shows a greater decrease in visceral fat tissue. These results are significant (p≤.05).
Conclusion: We found that calorie restriction has a greater effect on weight loss than exercise. But in fact, aerobic exercise had a better effect on reducing visceral fat tissue compared to calorie restriction. This shows the superiority of aerobic exercise in insulin sensitivity and diabetes.
Keywords