The impact of concurrent and high-intensity interval aquatic exercises on indicators of renal function in high-fat diet-induced obese rats
Poster Presentation
Paper ID : 1426-SSRC
Authors
1MSC ,Sport Physiology Department, Exercise science faculty, Hakim Sabzevari university. Sabzevar. Iran.
2Associate Professor, Sport Physiology Department, Exercise science faculty, Hakim Sabzevari university. Sabzevar. Iran
3MSC ,Sport Physiology Department, Exercise science faculty, Hakim Sabzevari university. Sabzevar. Iran
Abstract
Background: Obesity, characterized as a multifactorial metabolic syndrome, has been scientifically substantiated to exhibit a significant correlation with the spectrum of chronic renal disorders.
Objective: The aim of this study was to determine the effect of concurrent training (resistance endurance) and high-intensity interval training in water on the indicators of renal function in rats made obese through a high-fat diet.
Methodology: 24 male Wistar rats were randomly divided into four groups: 1) Control (healthy with standard diet), 2) High-fat diet (obese), 3) High-fat diet with concurrent training, and 4) High-fat diet with high-intensity interval training. Obesity was induced over ten weeks with a 45% high-fat diet. The groups underwent specific training five days per week for eight weeks in a specialized aquatic environment. After 48 hours post-training, blood samples were collected from the rats' hearts in a fasted state for biochemical analysis. Shapiro-Wilk, Levene's test, one-way ANOVA, Kruskal-Wallis, and post-hoc Tukey and Games-Howell tests were used for analysis with a significance level of p < 0.05.
Results: Groups showed significant differences in urea, creatinine, albumin, triglycerides, cholesterol, and fasting glucose (p < 0.05). Urea levels were reduced in concurrent group compared to obese control (p = 0.001). The concurrent group and the obese control did not have any significant differences in creatinine (p = 0.078), but there was a decrease in high-intensity compared to the obese control ( p = 0.025)..Urea, creatinine, and albumin levels were lower in the healthy group than the obese group (p = 0.001). Albumin was significantly lower in concurrent group vs. obese control (p = 0.001). Exercise groups had lower levels of triglycerides and cholesterol than obese control (p = 0.001). The healthy group had lower cholesterol levels than the obese control (p = 0.028). The concurrent group had significantly lower fasting glucose than the obese control. (p = 0.001). Additionally, high-intensity group showed significant fasting glucose reduction compared to obese control (p = 0.001).
Conclusion: Aquatic exercises may effectively reduce weight, fasting blood glucose, lipid profiles, and obesity-related renal function deterioration, with parallel exercises being slightly more effective.
Objective: The aim of this study was to determine the effect of concurrent training (resistance endurance) and high-intensity interval training in water on the indicators of renal function in rats made obese through a high-fat diet.
Methodology: 24 male Wistar rats were randomly divided into four groups: 1) Control (healthy with standard diet), 2) High-fat diet (obese), 3) High-fat diet with concurrent training, and 4) High-fat diet with high-intensity interval training. Obesity was induced over ten weeks with a 45% high-fat diet. The groups underwent specific training five days per week for eight weeks in a specialized aquatic environment. After 48 hours post-training, blood samples were collected from the rats' hearts in a fasted state for biochemical analysis. Shapiro-Wilk, Levene's test, one-way ANOVA, Kruskal-Wallis, and post-hoc Tukey and Games-Howell tests were used for analysis with a significance level of p < 0.05.
Results: Groups showed significant differences in urea, creatinine, albumin, triglycerides, cholesterol, and fasting glucose (p < 0.05). Urea levels were reduced in concurrent group compared to obese control (p = 0.001). The concurrent group and the obese control did not have any significant differences in creatinine (p = 0.078), but there was a decrease in high-intensity compared to the obese control ( p = 0.025)..Urea, creatinine, and albumin levels were lower in the healthy group than the obese group (p = 0.001). Albumin was significantly lower in concurrent group vs. obese control (p = 0.001). Exercise groups had lower levels of triglycerides and cholesterol than obese control (p = 0.001). The healthy group had lower cholesterol levels than the obese control (p = 0.028). The concurrent group had significantly lower fasting glucose than the obese control. (p = 0.001). Additionally, high-intensity group showed significant fasting glucose reduction compared to obese control (p = 0.001).
Conclusion: Aquatic exercises may effectively reduce weight, fasting blood glucose, lipid profiles, and obesity-related renal function deterioration, with parallel exercises being slightly more effective.
Keywords