Changes of Irisin and cognitive performance in response to exercise training

Poster Presentation
Paper ID : 1439-SSRC
Authors
1گروه تربیت بدنی دانشکده علوم اجتماعی دانشگاه بین المللی امام خمینی
2گروه آموزشی تربیت بدنی دانشگاه صنعتی امیرکبیر
Abstract
Aim Irisin is an indices of cognitive performance. Considering the positive effect of sports training on the expression Irisin in plasma, the present study seeks to investigate the effect of six weeks of swimming until exhustion on the changes of Irisin in brain tissue and cognitive performance. Methods: Therefore, 20 rats (age 8 weeks, weight 250 gr ± 30) were purchased from Pasteur Institute and after two weeks of familiarization with the standard animal environment in the laboratory and training protocol, they were randomly divided into two training and control groups. Each group included 10 male adult Wistar rats. Then the cognitive performance test. While during the implementation protocol, the control group continued their life in the laboratory, the training group performed six weeks of swimming exercises. 48 hours after the last training session, the rats were anesthetized and sacrificed, and their brain tissue was taken And for data analysis were sent to the laboratory. the Real-time PCR method was used to measure irisin gene expression. Independent t-test was used to analyze the findings. Results: The results of the data showed that six weeks swimming training up to exhustion caused a significant increase in brain tissue irisin levels compared to the control group (p<005, respectively). Also, the cognitive performance of the training group has improved significantly compared to the control group (p<001). Conclusions: seems that part of the positive changes in cognitive performance in response six weeks swimming up to exhustion occurs with changes in irisin and BDNF in brain cells.
Keywords