Efficacy of a period of home base aerobic training on mood status and fatigue in women with RRMS

Poster Presentation
Paper ID : 1606-SSRC
Authors
1گروه فیزیولوژی ورزشی، دانشکده تربیت بدنی، دانشگاه گیلان، رشت، گیلان، ایران
2گروه فیزیولوژی ورزشی، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه گیلان، رشت، گیلان، ایران
3گروه علوم اعصاب، دانشکده پزشکی، دانشگاه علوم پزشگی گیلان، رشت، گیلان، ایران
Abstract
Abstract
Background:
Multiple sclerosis (MS) ranks as the third most common cause of neurological disability, with relapsing-remitting MS (RRMS) identified as the most prevalent subclass. Individuals with MS face numerous challenges, serving as a significant barrier to daily activities. Increasing exercise activities namely aerobic training enhances individuals' energy levels throughout the day, contributing to an improved quality of life, enhanced mood, and better social interactions. The significance of this cannot be overlooked, especially for individuals with MS.

Objective:
This clinical study aimed to investigate the effects of aerobic exercises over an 8-week period on anxiety, mood in women with relapsing-remitting MS.

Methodology:
The clinical study involved 20 female participants with relapsing-remitting MS, aged 20 to 50, exhibiting disability scores ranging from 0 to 5.5. Participants were randomly assigned to either the aerobic exercises exercise group (10 participants) or the control group (10 participants). The 8-week exercise protocol, conducted two days a week, included walking (home-base). The duration of each patient's walk is determined based on his physical condition, starting from 10 minutes, and reaching 30 minutes a day in 8 weeks, with instructors ensuring exercise quality through video contact in each session. Anxiety and mood questionnaires were administered on days 10 and 11 of the menstrual cycle.

Results:
This study showed that 8 weeks of aerobic training has positive effects on mood states, including sociability, activity level, reduction of fatigue and fear(p<0.05). In addition, it led to a significant difference between group anxiety as well as significant increase in serum levels of cortisol(p<0.05).

Conclusion:
It can be concluded that aerobic exercise, despite increased anxiety levels can have a tremendous impact on mood status and fatigue in women with RRMS.
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