Poster Presentation

Paper ID : 1688-SSRC

فاقد وابستگی

Introduction: Inflammation is a natural biological response of the body to physical, chemical or biological stimuli. The consumption of flavonoids and the use of food supplements, including certain such as some vitamins and herbs have been shown to potentially reduce free radicals and inflammatory reactions. Background: Therefore, the aim of this study is to investigate the effects of orally consuming powdered Melissa officinalis (MO) on biomarkers of inflammatory factors caused by exhaustive exercise in active men. Materials and Methods: 12 trained men (age, 25±3 years; body mass index, 24.8±2.4 kg/m2) participated in two activity sessions: placebo and MO. The exercise protocol involved increasing activity through running on a treadmill until exhaustion. Blood samples were collected before test, immediately after the test, and then the subjects consumed either powdered MO supplement or placebo. Two hours and 24 hours after taking the supplement, third and fourth blood samples were collected to measure IL-6, TNF-α and CRP indices. Results: The results showed that exhaustive exercise had significant effects on the plasma levels of TNF-α (F1,9 = 16.55 and p = 0.03), IL -6 (F1,9=20.01 and p=0.002) and CRP (F1,9=17.87 and p=0.002). Comparing the data between the placebo and supplement sessions revealed a significant reduction of plasma levels of TNF-α (F1.2,10.8=14.34 and p=0.01), IL-6 (F1.3,12.4=11.30 and p=0.05) and CRP (F3, 27=78/11 and p=0.02) within 24 hours after sports activity and receiving MO supplement. Conclusion: Based on the results of this research, increasing aerobic activity to the point of stagnation has a significant and positive effect on inflammatory indicators. Moreover, the supplement of MO can helps the immune system to reduce inflammation after exercise.

Melissa officinalis; Inflammatory factors; exhaustive exercise; Men