Comparison of the Effects of Upper Body, Lower Body, and Combined Resistance Training on Inflammatory and Muscle Markers in Overweight Men
Poster Presentation
Paper ID : 1796-SSRC
Authors
1دانشجوی دکترای فیزیولوژی ورزشی دانشگاه اصفهان
2استاد گروه فیزیولوژی ورزشی دانشکده علوم ورزشی دانشگاه اصفهان، اصفهان، ایران
Abstract
Background and purpose: In today's sedentary lifestyle, obesity and overweight have increased, leading to an elevated risk of developing some chronic diseases. One factor identifying obesity as a risk factor for chronic diseases is the induction of chronic inflammation in the body. Chronic inflammation disrupts muscle contractions, reduces strength, diminishes protein synthesis, and consequently leads to a decrease in muscle mass. resistance training improves inflammatory markers and induces changes in certain muscular markers, such as decreasing myostatin levels and increasing follistatin levels preventing then muscle atrophy, and promoting muscle mass. The present study examined whether differential responses in follistatin, myostatin, CRP, and adiponectin occur based on the amount of active musculature in a resistance training program in overweight men. Method: Sixty overweight men (BMI= 28.44 ± 1.43 kg/m2) were randomly assigned to three resistance training groups: upper body (n=15), lower body (n=15), combined (n=15), and a control group (n=15). The training protocol consisted of three exercise sessions per week for 12 weeks. Blood samples were obtained at baseline and 48 hours after the final session of the training program. Results: Muscle mass significantly increased (p < 0.05) following upper body, lower body, and combined (UB + LB) compared to no changes after control. Serum follistatin and adiponectin increased and serum CRP decreased in all experimental groups; while serum myostatin decreased in the lower body and combined (UB+LB) but not in the upper body group. Further, improvement in concentration following training was larger between combined (UB+LB) and either lower body or upper body alone for myostatin, follistatin, and adiponectin.
Discussion and Conclusions: Both upper body and lower body resistance training increase muscle mass and alter the serum level of muscular and inflammatory markers. however, the changes in adiponectin, myostatin, and follistatin are larger if the upper body and lower body are combined. The adaptation to resistance training of myostatin, follistatin, and adiponectin may rely on the volume of muscle mass activated during training.
Discussion and Conclusions: Both upper body and lower body resistance training increase muscle mass and alter the serum level of muscular and inflammatory markers. however, the changes in adiponectin, myostatin, and follistatin are larger if the upper body and lower body are combined. The adaptation to resistance training of myostatin, follistatin, and adiponectin may rely on the volume of muscle mass activated during training.
Keywords