The effect of four training methods on the Copeptin expression in the left ventricle of male wistar rats
Poster Presentation
Paper ID : 1885-SSRC
Authors
1PhD Exercise Physiology,
2Msc Exercise Physiology
Abstract
The effect of four training methods on the Copeptin proadrenomedullin expression in the left ventricle of male wistar rats.
Background & Aims: Considering the importance of preventing the risk factor in heart disease and lack of sufficient information about the effect of exercise training on copeptin expression, this study aimed to investigate the effect of four training methods on the copeptin and expression in the left ventricle of male Wistar rats. Materials & Methods: In this experimental study, 40 male Wistar rats with the age of 8-weeks and an average weight of 237±33 grams were randomly divided into 5 groups: control, moderate-intensity training, high-intensity training, high-intensity interval training, and moderate-intensity swimming training. The training programs in experimental groups were performed for 8 weeks (5 days a week). Expression of research genes was determined by real-time polymerase chain reaction. To analyze the data, one way ANOVA and bonferroni were used at a significance level of p≤ 0.05. Results: Copeptin expressions in each training group decreased significantly compared to the control group (p= 0.001, p= 0.001). Also, Copeptin and expression increased significantly in HIIT and HIT groups compared to ST and MIT groups (p= 0.001, p= 0.001). Conclusion: All of the four exercise training methods were able to reduce the expression of the studied genes, and make favorable changes in reducing the consequences of cardiac tissue injury. However, swimming exercises seem to have more favorable effects with regard to non-weight bearing property, although further research is needed.
Copeptin,, Exercise training, Heart ventricle
Background & Aims: Considering the importance of preventing the risk factor in heart disease and lack of sufficient information about the effect of exercise training on copeptin expression, this study aimed to investigate the effect of four training methods on the copeptin and expression in the left ventricle of male Wistar rats. Materials & Methods: In this experimental study, 40 male Wistar rats with the age of 8-weeks and an average weight of 237±33 grams were randomly divided into 5 groups: control, moderate-intensity training, high-intensity training, high-intensity interval training, and moderate-intensity swimming training. The training programs in experimental groups were performed for 8 weeks (5 days a week). Expression of research genes was determined by real-time polymerase chain reaction. To analyze the data, one way ANOVA and bonferroni were used at a significance level of p≤ 0.05. Results: Copeptin expressions in each training group decreased significantly compared to the control group (p= 0.001, p= 0.001). Also, Copeptin and expression increased significantly in HIIT and HIT groups compared to ST and MIT groups (p= 0.001, p= 0.001). Conclusion: All of the four exercise training methods were able to reduce the expression of the studied genes, and make favorable changes in reducing the consequences of cardiac tissue injury. However, swimming exercises seem to have more favorable effects with regard to non-weight bearing property, although further research is needed.
Copeptin,, Exercise training, Heart ventricle
Keywords
Proceeding Title [Persian]
The effect of four training methods on the Copeptin expression in the left ventricle of male wistar rats
Authors [Persian]