The Effect of L-Carnitine Supplementation on Some Antioxidant Indexes Following to Resistance Exercice in Over-Weight Non-Athlete Women

Poster Presentation
Paper ID : 1894-SSRC
Authors
استادیار گروه تربیت بدنی و علوم ورزشی دانشگاه آزاد اسلامی واحد مریوان
Abstract
Background and Objective: The aim of this study was to investigate of short-term L carnitine supplementation on myeloperoxidase (MPO) and catalase (CAT) in response to an acute high intensity resistance exercise in non-athletic over-weight women. Materials and Methods: To this end, among voluntaries participants, 20 men was selected and randomly divided into supplement (n=10) and placebo (n=10) groups. Each group was given either L-carnitine or a placebo (maltodextrine) in a double blind manner to be taken orally for a week. Then, after consuming supplement or placebo for a week (2 capsules daily; each capsule contain 1000 mg l carnitine of maltodextrine) each participant performed an acute resistance exercise. The resistance training session consisted of 5 exercises with 85 percent of 1 repetition maximum. Blood samples were taken in 4 stages; before supplement, before resistance exercise, immediately and 24 hours after exercise cessation and used for analyzing MPO and CAT. Results: The results showed that the acute resistance exercise increased MPO concentration and decreased CAT immediately after exercise session. On the other hand, consuming L carnitine decreased MPO concentration at rest and prevented an increase in MPO immediately after exercise. In addition, L carnitine lowered MPO concentration more than basal level at 24 hours after the acute exercise. Also, L carnitine increased CAt concentration at 24 hours after cessation of the acute resistance exercise. Conclusion: The results suggest that consuming L carnitine can prevent an increase in MPO induced by an acute resistance exercise. Also L carnitine stimulates increase in CAT at 24 hours after resistance exercise that probably has an important role in increase of antioxidant indexes, muscle regeneration and recovery after exercise.
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