The effect of transcranial direct stimulation of DLPFC with aerobic exercise on appetite, glucose and insulin resistance in obese men
Poster Presentation
Paper ID : 2165-SSRC
Authors
1دانشگاه ازاداسلامی واحدخرم اباد
2استادیار،دانشگاه آزاد اسلامی، واحد خرم آباد
Abstract
Background: Hunger and food intake are regulated by different hierarchical processes that rely on distinct but intertwined neural circuits, such as homeostatic and reward circuits, and cognitive domains. In particular, a key region primarily involved in the regulation of impulsivity and binge eating is the dorsolateral prefrontal cortex (DLPFC), which has been shown to have reduced activation in obese patients. Therefore, it prevents modification of lifestyle habits (for example, food consumption and physical activity).
Purpose: The purpose of the current study was to examine the effect of transcranial direct stimulation of DLPFC with aerobic exercise on appetite, glucose and insulin resistance in obese men.
Methodology: In this semi-experimental study with a pre-test-post-test design, among obese men (body mass index above 30 kg/m2) in Nahavand city, 30 people were selected as voluntary participation and randomly divided into two groups: real stimulation of DLPFC was combined with aerobic exercise and sham stimulation of DLPFC was combined with aerobic exercise. , and then the participants completed the food cravings questionnaire. The training phase will last 8 weeks and 3 sessions each week. In each session, the participants of the real DLPFC stimulation sat on a chair in a quiet room and DLPFC stimulation (anode F3 and cathode F4) was performed for 20 minutes with an intensity of 2 mA. After the stimulation, they performed the related aerobic exercise, while the DLPFC sham stimulation participants performed the related aerobic exercise after 20 minutes of sham stimulation (cutting the electrodes). The data was analyzed using the covariance test.
Results: The results showed that real stimulation of DLPFC compared to sham stimulation of DLPFC with aerobic exercise improved appetite and reduced insulin resistance and fasting glucose in obese men.
Conclusion: In general, the results of the present research emphasize the importance of DLPFC stimulation as a complementary method along with physical activity in improving obesity.
Purpose: The purpose of the current study was to examine the effect of transcranial direct stimulation of DLPFC with aerobic exercise on appetite, glucose and insulin resistance in obese men.
Methodology: In this semi-experimental study with a pre-test-post-test design, among obese men (body mass index above 30 kg/m2) in Nahavand city, 30 people were selected as voluntary participation and randomly divided into two groups: real stimulation of DLPFC was combined with aerobic exercise and sham stimulation of DLPFC was combined with aerobic exercise. , and then the participants completed the food cravings questionnaire. The training phase will last 8 weeks and 3 sessions each week. In each session, the participants of the real DLPFC stimulation sat on a chair in a quiet room and DLPFC stimulation (anode F3 and cathode F4) was performed for 20 minutes with an intensity of 2 mA. After the stimulation, they performed the related aerobic exercise, while the DLPFC sham stimulation participants performed the related aerobic exercise after 20 minutes of sham stimulation (cutting the electrodes). The data was analyzed using the covariance test.
Results: The results showed that real stimulation of DLPFC compared to sham stimulation of DLPFC with aerobic exercise improved appetite and reduced insulin resistance and fasting glucose in obese men.
Conclusion: In general, the results of the present research emphasize the importance of DLPFC stimulation as a complementary method along with physical activity in improving obesity.
Keywords